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Differential regulations of fibronectin and laminin in Smad2 activation in vascular endothelial cells in response to disturbed flow

BACKGROUND: Atherosclerosis occurs in arterial curvatures and branches, where the flow is disturbed with low and oscillatory shear stress (OSS). The remodeling and alterations of extracellular matrices (ECMs) and their composition is the critical step in atherogenesis. In this study, we investigated...

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Detalles Bibliográficos
Autores principales: Yang, Tung-Lin, Lee, Pei-Ling, Lee, Ding-Yu, Wang, Wei-Li, Wei, Shu-Yi, Lee, Chih-I, Chiu, Jeng-Jiann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749020/
https://www.ncbi.nlm.nih.gov/pubmed/29295709
http://dx.doi.org/10.1186/s12929-017-0402-4