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Differential regulations of fibronectin and laminin in Smad2 activation in vascular endothelial cells in response to disturbed flow
BACKGROUND: Atherosclerosis occurs in arterial curvatures and branches, where the flow is disturbed with low and oscillatory shear stress (OSS). The remodeling and alterations of extracellular matrices (ECMs) and their composition is the critical step in atherogenesis. In this study, we investigated...
Autores principales: | Yang, Tung-Lin, Lee, Pei-Ling, Lee, Ding-Yu, Wang, Wei-Li, Wei, Shu-Yi, Lee, Chih-I, Chiu, Jeng-Jiann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749020/ https://www.ncbi.nlm.nih.gov/pubmed/29295709 http://dx.doi.org/10.1186/s12929-017-0402-4 |
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