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Pirfenidone Inhibits Proliferation and Promotes Apoptosis of Hepatocellular Carcinoma Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is the most important cause of cancer-related deaths worldwide. Pirfenidone is an orally available small molecule with therapeutic potential for fibrotic diseases. MATERIAL/METHODS: In this study, we analyzed the effects of different pirfenidone concentrati...

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Detalles Bibliográficos
Autores principales: Zou, Wei-Jie, Huang, Zhi, Jiang, Tian-Peng, Shen, Ya-Ping, Zhao, An-Su, Zhou, Shi, Zhang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749136/
https://www.ncbi.nlm.nih.gov/pubmed/29276937
http://dx.doi.org/10.12659/MSM.907891