Pioglitazone Attenuates Atherosclerosis in Diabetic Mice by Inhibition of Receptor for Advanced Glycation End-Product (RAGE) Signaling

BACKGROUND: Peroxisome proliferator-activated receptor-γ (PPAR-γ) exhibits anti-inflammatory and anti-diabetic properties, and is protective against cardiovascular diseases. This study aimed to determine the effects of a PPAR-γ agonist pioglitazone on atherogenesis in an ApoE knockout mouse (ApoE(−/...

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Detalles Bibliográficos
Autores principales: Gao, Hongli, Li, Hongwei, Li, Weiping, Shen, Xuhua, Di, Beibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749137/
https://www.ncbi.nlm.nih.gov/pubmed/29278639
http://dx.doi.org/10.12659/MSM.907401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749137/
https://www.ncbi.nlm.nih.gov/pubmed/29278639
http://dx.doi.org/10.12659/MSM.907401

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