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ESCO1/2's roles in chromosome structure and interphase chromatin organization

ESCO1/2 acetyltransferases mediating SMC3 acetylation and sister chromatid cohesion (SCC) are differentially required for genome integrity and development. Here we established chicken DT40 cell lines with mutations in ESCO1/2, SMC3 acetylation, and the cohesin remover WAPL. Both ESCO1 and ESCO2 prom...

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Detalles Bibliográficos
Autores principales: Kawasumi, Ryotaro, Abe, Takuya, Arakawa, Hiroshi, Garre, Massimiliano, Hirota, Kouji, Branzei, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749162/
https://www.ncbi.nlm.nih.gov/pubmed/29196537
http://dx.doi.org/10.1101/gad.306084.117

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