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Discovery of noncanonical translation initiation sites through mass spectrometric analysis of protein N termini

Translation initiation generally occurs at AUG codons in eukaryotes, although it has been shown that non-AUG or noncanonical translation initiation can also occur. However, the evidence for noncanonical translation initiation sites (TISs) is largely indirect and based on ribosome profiling (Ribo-seq...

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Detalles Bibliográficos
Autores principales: Na, Chan Hyun, Barbhuiya, Mustafa A., Kim, Min-Sik, Verbruggen, Steven, Eacker, Stephen M., Pletnikova, Olga, Troncoso, Juan C., Halushka, Marc K., Menschaert, Gerben, Overall, Christopher M., Pandey, Akhilesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749180/
https://www.ncbi.nlm.nih.gov/pubmed/29162641
http://dx.doi.org/10.1101/gr.226050.117