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Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI
DNA methylation is a well-known epigenetic modification that plays a crucial role in gene regulation, but genome-wide analysis of DNA methylation remains technically challenging and costly. DNA methylation-dependent restriction enzymes can be used to restrict CpG methylation analysis to methylated r...
Autores principales: | Boers, Ruben, Boers, Joachim, de Hoon, Bas, Kockx, Christel, Ozgur, Zeliha, Molijn, Anco, van IJcken, Wilfred, Laven, Joop, Gribnau, Joost |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749185/ https://www.ncbi.nlm.nih.gov/pubmed/29222086 http://dx.doi.org/10.1101/gr.222885.117 |
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