Postmortem Findings in Patient with Guillain-Barré Syndrome and Zika Virus Infection

Postmortem examination results of a patient with Guillain-Barré syndrome and confirmed Zika virus infection revealed demyelination of the sciatic and cranial IV nerves, providing evidence of the acute demyelinating inflammatory polyneuropathy Guillain-Barré syndrome variant. Lack of evidence of Zika...

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Detalles Bibliográficos
Autores principales: Dirlikov, Emilio, Torres, José V., Martines, Roosecelis Brasil, Reagan-Steiner, Sarah, Pérez, George Venero, Rivera, Aidsa, Major, Chelsea, Matos, Desiree, Muñoz-Jordan, Jorge, Shieh, Wun-Ju, Zaki, Sherif R., Sharp, Tyler M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749436/
https://www.ncbi.nlm.nih.gov/pubmed/29261094
http://dx.doi.org/10.3201/eid2401.171331
Descripción
Sumario:Postmortem examination results of a patient with Guillain-Barré syndrome and confirmed Zika virus infection revealed demyelination of the sciatic and cranial IV nerves, providing evidence of the acute demyelinating inflammatory polyneuropathy Guillain-Barré syndrome variant. Lack of evidence of Zika virus in nervous tissue suggests that pathophysiology was antibody mediated without neurotropism.

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