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The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1
BACKGROUND: Aberrant expression of miR-199a has been frequently reported in cancer studies; however, its role in renal cell carcinoma (RCC) has not been examined in detail. RESULTS: Here, we showed that miR-199a was downregulated in RCC and associated with poor prognostic phenotype. Using luciferase...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749572/ https://www.ncbi.nlm.nih.gov/pubmed/29343969 http://dx.doi.org/10.2147/OTT.S147184 |