The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1

BACKGROUND: Aberrant expression of miR-199a has been frequently reported in cancer studies; however, its role in renal cell carcinoma (RCC) has not been examined in detail. RESULTS: Here, we showed that miR-199a was downregulated in RCC and associated with poor prognostic phenotype. Using luciferase...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Li, Peng, Ding, Zhen, Wang, Huili, Wang, Junye, Han, Lei, Ding, Shangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749572/
https://www.ncbi.nlm.nih.gov/pubmed/29343969
http://dx.doi.org/10.2147/OTT.S147184

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