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Exploring the role of L209 residue in the active site of NDM-1 a metallo-β-lactamase

BACKGROUND: New Delhi Metallo-β-Lactamase (NDM-1) is one of the most recent additions to the β-lactamases family. Since its discovery in 2009, NDM-1 producing Enterobacteriaceae have disseminated globally. With few effective antibiotics against NDM-1 producers, there is an urgent need to design new...

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Detalles Bibliográficos
Autores principales: Marcoccia, Francesca, Leiros, Hanna-Kirsti S., Aschi, Massimiliano, Amicosante, Gianfranco, Perilli, Mariagrazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749715/
https://www.ncbi.nlm.nih.gov/pubmed/29293526
http://dx.doi.org/10.1371/journal.pone.0189686