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Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

Glucagon-like peptide 1 (GLP-1) stimulated insulin secretion has a considerable heritable component as estimated from twin studies, yet few genetic variants influencing this phenotype have been identified. We performed the first genome-wide association study (GWAS) of GLP-1 stimulated insulin secret...

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Detalles Bibliográficos
Autores principales:	Gudmundsdottir, Valborg, Pedersen, Helle Krogh, Allebrandt, Karla Viviani, Brorsson, Caroline, van Leeuwen, Nienke, Banasik, Karina, Mahajan, Anubha, Groves, Christopher J., van de Bunt, Martijn, Dawed, Adem Y., Fritsche, Andreas, Staiger, Harald, Simonis-Bik, Annemarie M. C., Deelen, Joris, Kramer, Mark H. H., Dietrich, Axel, Hübschle, Thomas, Willemsen, Gonneke, Häring, Hans-Ulrich, de Geus, Eco J. C., Boomsma, Dorret I., Eekhoff, Elisabeth M. W., Ferrer, Jorge, McCarthy, Mark I., Pearson, Ewan R., Gupta, Ramneek, Brunak, Søren, ‘t Hart, Leen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749727/ https://www.ncbi.nlm.nih.gov/pubmed/29293525 http://dx.doi.org/10.1371/journal.pone.0189886

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