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Upstream signalling of mTORC1 and its hyperactivation in type 2 diabetes (T2D)

Mammalian target of rapamycin complex 1 (mTORC1) plays a major role in cell growth, proliferation, polarity, differentiation, development, and controls transitioning between anabolic and catabolic states of the cell. It collects almost all extracellular and intracellular signals from growth factors,...

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Detalles Bibliográficos
Autores principales: Ali, Muhammad, Bukhari, Shazia Anwer, Lee, Han-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749905/
https://www.ncbi.nlm.nih.gov/pubmed/29187279
http://dx.doi.org/10.5483/BMBRep.2017.50.12.206