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Upstream signalling of mTORC1 and its hyperactivation in type 2 diabetes (T2D)
Mammalian target of rapamycin complex 1 (mTORC1) plays a major role in cell growth, proliferation, polarity, differentiation, development, and controls transitioning between anabolic and catabolic states of the cell. It collects almost all extracellular and intracellular signals from growth factors,...
Autores principales: | Ali, Muhammad, Bukhari, Shazia Anwer, Lee, Han-Woong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749905/ https://www.ncbi.nlm.nih.gov/pubmed/29187279 http://dx.doi.org/10.5483/BMBRep.2017.50.12.206 |
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