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Anti-inflammatory and anti-oxidative effects of 3-(naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride on β-amyloid-induced microglial activation

We aimed to assess the anti-inflammatory and antioxidative properties of KHG26792, a novel azetidine derivative, in amyloid β (Aβ)-treated primary microglial cells. KHG26792 attenuated the Aβ-induced production of inflammatory mediators such as IL-6, IL-1β, TNF-α, and nitric oxide. The levels of pro...

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Detalles Bibliográficos
Autores principales:	Yang, Seung-Ju, Kim, Jiae, Lee, Sang Eun, Ahn, Jee-Yin, Choi, Soo Young, Cho, Sung-Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749910/ https://www.ncbi.nlm.nih.gov/pubmed/29065971 http://dx.doi.org/10.5483/BMBRep.2017.50.12.189

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