Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

The public health threat posed by a looming ‘post-antibiotic’ era necessitates new approaches to antibiotic discovery. Drug development has typically avoided exploitation of membrane-binding properties, in contrast to nature’s control of biological pathways via modulation of membrane-associated prot...

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Detalles Bibliográficos
Autores principales: Blaskovich, Mark A. T., Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G., Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E., Sidjabat, Hanna E., Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R., Beevers, Andrew P. G., Smith, Richard A. G., Roberts, Jason A., Paterson, David L., Cooper, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750218/
https://www.ncbi.nlm.nih.gov/pubmed/29295973
http://dx.doi.org/10.1038/s41467-017-02123-w

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