Network connectivity determines cortical thinning in early Parkinson’s disease progression

Here we test the hypothesis that the neurodegenerative process in Parkinson’s disease (PD) moves stereotypically along neural networks, possibly reflecting the spread of toxic alpha-synuclein molecules. PD patients (n = 105) and matched controls (n = 57) underwent T1-MRI at entry and 1 year later as...

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Detalles Bibliográficos
Autores principales: Yau, Y., Zeighami, Y., Baker, T. E., Larcher, K., Vainik, U., Dadar, M., Fonov, V. S., Hagmann, P., Griffa, A., Mišić, B., Collins, D. L., Dagher, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750227/
https://www.ncbi.nlm.nih.gov/pubmed/29295991
http://dx.doi.org/10.1038/s41467-017-02416-0

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