Macrophages orchestrate breast cancer early dissemination and metastasis

Cancer cell dissemination during very early stages of breast cancer proceeds through poorly understood mechanisms. Here we show, in a mouse model of HER2(+) breast cancer, that a previously described sub-population of early-evolved cancer cells requires macrophages for early dissemination. Depletion...

Descripción completa

Detalles Bibliográficos
Autores principales: Linde, Nina, Casanova-Acebes, Maria, Sosa, Maria Soledad, Mortha, Arthur, Rahman, Adeeb, Farias, Eduardo, Harper, Kathryn, Tardio, Ethan, Reyes Torres, Ivan, Jones, Joan, Condeelis, John, Merad, Miriam, Aguirre-Ghiso, Julio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750231/
https://www.ncbi.nlm.nih.gov/pubmed/29295986
http://dx.doi.org/10.1038/s41467-017-02481-5

Ejemplares similares

Ejemplares similares