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ATG8 Is Essential Specifically for an Autophagy-Independent Function in Apicoplast Biogenesis in Blood-Stage Malaria Parasites

Plasmodium parasites and related pathogens contain an essential nonphotosynthetic plastid organelle, the apicoplast, derived from secondary endosymbiosis. Intriguingly, a highly conserved eukaryotic protein, autophagy-related protein 8 (ATG8), has an autophagy-independent function in the apicoplast....

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Detalles Bibliográficos
Autores principales: Walczak, Marta, Ganesan, Suresh M., Niles, Jacquin C., Yeh, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750400/
https://www.ncbi.nlm.nih.gov/pubmed/29295911
http://dx.doi.org/10.1128/mBio.02021-17