O-Mannosylation of Proteins Enables Histoplasma Yeast Survival at Mammalian Body Temperatures

The ability to grow at mammalian body temperatures is critical for pathogen infection of humans. For the thermally dimorphic fungal pathogen Histoplasma capsulatum, elevated temperature is required for differentiation of mycelia or conidia into yeast cells, a step critical for invasion and replicati...

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Detalles Bibliográficos
Autores principales: Garfoot, Andrew L., Goughenour, Kristie D., Wüthrich, Marcel, Rajaram, Murugesan V. S., Schlesinger, Larry S., Klein, Bruce S., Rappleye, Chad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750402/
https://www.ncbi.nlm.nih.gov/pubmed/29295913
http://dx.doi.org/10.1128/mBio.02121-17

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