Cargando…

Neural Differentiation Is Inhibited through HIF1α/β-Catenin Signaling in Embryoid Bodies

Extensive research in the field of stem cells and developmental biology has revealed evidence of the role of hypoxia as an important factor regulating self-renewal and differentiation. However, comprehensive information about the exact hypoxia-mediated regulatory mechanism of stem cell fate during e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Večeřa, Josef, Kudová, Jana, Kučera, Jan, Kubala, Lukáš, Pacherník, Jiří
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750467/ https://www.ncbi.nlm.nih.gov/pubmed/29422917 http://dx.doi.org/10.1155/2017/8715798

Ejemplares similares

Hypoxia favors myosin heavy chain beta gene expression in an Hif-1alpha-dependent manner
por: Binó, Lucia, et al.
Publicado: (2017)

HIF-1alpha Deficiency Attenuates the Cardiomyogenesis of Mouse Embryonic Stem Cells
por: Kudová, Jana, et al.
Publicado: (2016)

Apocynin and Diphenyleneiodonium Induce Oxidative Stress and Modulate PI3K/Akt and MAPK/Erk Activity in Mouse Embryonic Stem Cells
por: Kučera, Jan, et al.
Publicado: (2016)

Hypoxia Downregulates MAPK/ERK but Not STAT3 Signaling in ROS-Dependent and HIF-1-Independent Manners in Mouse Embryonic Stem Cells
por: Kučera, Jan, et al.
Publicado: (2017)

The acceleration of cardiomyogenesis in embryonic stem cells in vitro by serum depletion does not increase the number of developed cardiomyocytes
por: Radaszkiewicz, Katarzyna Anna, et al.
Publicado: (2017)

Cell Mechanics in Embryoid Bodies
por: Zeevaert, Kira, et al.
Publicado: (2020)

MAPK p38alpha Kinase Influences Haematopoiesis in Embryonic Stem Cells
por: Štefková, Kateřina, et al.
Publicado: (2019)

Compartmentalized embryoid body culture for induction of spatially patterned differentiation
por: Kaneda, Shohei, et al.
Publicado: (2017)

Hyperthermia Disturbs and Delays Spontaneous Differentiation of Human Embryoid Bodies
por: Kwon, Ji Hyun, et al.
Publicado: (2020)

Resveratrol’s neural protective effects for the injured embryoid body and cerebral organoid
por: Wang, Yanli, et al.
Publicado: (2022)

Conductive Polymer PEDOT:PSS-Based Platform for Embryonic Stem-Cell Differentiation
por: Šafaříková, Eva, et al.
Publicado: (2022)

GSK-J4-Mediated Transcriptomic Alterations in Differentiating Embryoid Bodies
por: Mandal, Chanchal, et al.
Publicado: (2017)

Effect of cellular mass on chondrogenic differentiation during embryoid body formation
por: Lach, Michał Stefan, et al.
Publicado: (2018)

Differentiation of Mouse Embryonic Stem Cells into Endoderm without Embryoid Body Formation
por: Kim, Peter T. W., et al.
Publicado: (2010)

Microfabric Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells
por: Sato, Hiroki, et al.
Publicado: (2016)

In Vivo Osteogenic Differentiation of Human Embryoid Bodies in an Injectable in Situ-Forming Hydrogel
por: Kim, Da Yeon, et al.
Publicado: (2013)

Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies
por: Bhattacharya, Bhaskar, et al.
Publicado: (2005)

The role of extracellular matrix in the migration and differentiation of parietal endoderm from teratocarcinoma embryoid bodies
Publicado: (1987)

Human embryoid bodies as a 3D tissue model of the extracellular matrix and α-dystroglycanopathies
por: Nickolls, Alec R., et al.
Publicado: (2020)

Screening for Best Neuronal-Glial Differentiation Protocols of Neuralizing Agents Using a Multi-Sized Microfluidic Embryoid Body Array
por: Eilenberger, Christoph, et al.
Publicado: (2022)

Hypoxia is fine-tuned by Hif-1α and regulates mesendoderm differentiation through the Wnt/β-Catenin pathway
por: Shen, Xiaopeng, et al.
Publicado: (2022)

Extracellular Matrix Aggregates from Differentiating Embryoid Bodies as a Scaffold to Support ESC Proliferation and Differentiation
por: Goh, Saik-Kia, et al.
Publicado: (2013)

Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern
por: Kulinski, Tomasz M., et al.
Publicado: (2015)

Use of Long-term Cultured Embryoid Bodies May Enhance Cardiomyocyte Differentiation by BMP2
por: Kim, Yoon Young, et al.
Publicado: (2008)

A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo
por: Spangler, Abby, et al.
Publicado: (2018)

Differential Single Cell Responses of Embryonic Stem Cells Versus Embryoid Bodies to Gravity Mechanostimulation
por: Juran, Cassandra M., et al.
Publicado: (2022)

Correction: Extracellular Matrix Aggregates from Differentiating Embryoid Bodies as a Scaffold to Support ESC Proliferation and Differentiation
por: Goh, Saik-Kia, et al.
Publicado: (2013)

Integrated live imaging and molecular profiling of embryoid bodies reveals a synchronized progression of early differentiation
por: Boxman, Jonathan, et al.
Publicado: (2016)

Mitochondrial Fusion by M1 Promotes Embryoid Body Cardiac Differentiation of Human Pluripotent Stem Cells
por: Lees, Jarmon G., et al.
Publicado: (2019)

The Contribution of Y Chromosome Genes to Spontaneous Differentiation of Human Embryonic Stem Cells into Embryoid Bodies In Vitro
por: Nafian Dehkordi, Simin, et al.
Publicado: (2021)

Archetypal Architecture Construction, Patterning, and Scaling Invariance in a 3D Embryoid Body Differentiation Model
por: Gordeeva, Olga, et al.
Publicado: (2022)

HIF-1α Affects the Neural Stem Cell Differentiation of Human Induced Pluripotent Stem Cells via MFN2-Mediated Wnt/β-Catenin Signaling
por: Cui, Peng, et al.
Publicado: (2021)

Matrix Rigidity-Modulated Cardiovascular Organoid Formation from Embryoid Bodies
por: Shkumatov, Artem, et al.
Publicado: (2014)

Osteogenic Embryoid Body-Derived Material Induces Bone Formation In Vivo
por: Sutha, Ken, et al.
Publicado: (2015)

Trim33 regulates early maturation of mouse embryoid bodies in vitro
por: Rajderkar, Sudha, et al.
Publicado: (2017)

A standardized human embryoid body platform for the detection and analysis of teratogens
por: Flamier, Anthony, et al.
Publicado: (2017)

Adherent but Not Suspension-Cultured Embryoid Bodies Develop into Laminated Retinal Organoids
por: Radojevic, Bojana, et al.
Publicado: (2021)

In vitro differentiation of human embryonic stem cells to hemogenic endothelium and blood progenitors via embryoid body formation
por: Garcia-Alegria, Eva, et al.
Publicado: (2021)

The pro‐inflammatory signature of lipopolysaccharide in spontaneous contracting embryoid bodies differentiated from mouse embryonic stem cells
por: Scharmacher, Jennifer, et al.
Publicado: (2023)

Hypoxia and Extracellular Matrix Proteins Influence Angiogenesis and Lymphangiogenesis in Mouse Embryoid Bodies
por: Foskett, Andrea M., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_tq8cnj1tobqpk05rbt2imkp66m