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Complex roles of the stroma in the intrinsic resistance to gemcitabine in pancreatic cancer: where we are and where we are going

Pancreatic ductal adenocarcinoma (PDAC) is among the most devastating human malignancies. The poor clinical outcome in PDAC is partly attributed to a growth-permissive tumor microenvironment. In the PDAC microenvironment, the stroma is characterized by the development of extensive fibrosis, with str...

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Detalles Bibliográficos
Autores principales:	Liang, Chen, Shi, Si, Meng, Qingcai, Liang, Dingkong, Ji, Shunrong, Zhang, Bo, Qin, Yi, Xu, Jin, Ni, Quanxing, Yu, Xianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750480/ https://www.ncbi.nlm.nih.gov/pubmed/29611542 http://dx.doi.org/10.1038/emm.2017.255

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