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Hypertension in Non-Type 2 Diabetes in Isfahan, Iran: Incidence and Risk Factors
OBJECTIVE: To estimate the incidence of and risk factors for the development of hypertension (HTN) in people with T1D using routinely collected data. METHOD: The mean 16-year incidence of HTN was measured among 1,167 (557 men and 610 women) nonhypertensive patients with T1D from Isfahan Endocrine an...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750488/ https://www.ncbi.nlm.nih.gov/pubmed/29423321 http://dx.doi.org/10.1155/2017/3132729 |
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author | Janghorbani, Mohsen Aminorroaya, Ashraf Amini, Masoud |
author_facet | Janghorbani, Mohsen Aminorroaya, Ashraf Amini, Masoud |
author_sort | Janghorbani, Mohsen |
collection | PubMed |
description | OBJECTIVE: To estimate the incidence of and risk factors for the development of hypertension (HTN) in people with T1D using routinely collected data. METHOD: The mean 16-year incidence of HTN was measured among 1,167 (557 men and 610 women) nonhypertensive patients with T1D from Isfahan Endocrine and Metabolism Research Center outpatient clinics, Iran. HTN was defined as a systolic blood pressure (BP) of 140 mm Hg or higher and/or a diastolic BP 90 mm Hg or higher and/or use of antihypertensive medications. The mean (standard deviation [SD]) age of participants was 20.6 years (10.5 years) with a mean (SD) duration of diabetes of 3.6 years (4.8 years) at registration. RESULTS: The prevalence of HTN at baseline was 9.7% (95% CI: 8.2, 11.5). Among the 1,167 patients free of HTN at registration who attended the clinic at least twice in the period 1992–2016, the incidence of HTN was 9.6 (8.0 women and 11.3 men) per 1000 person-years based on 18,870 person-years of follow-up. Multivariate analyses showed that male gender, older age, higher triglyceride, and higher systolic BP were significantly and independently associated with the development of HTN in this population. CONCLUSION: These findings will help the identification of those patients with T1D at particular risk of HTN and strongly support the case for vigorous control of BP in patients with T1D. |
format | Online Article Text |
id | pubmed-5750488 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-57504882018-02-08 Hypertension in Non-Type 2 Diabetes in Isfahan, Iran: Incidence and Risk Factors Janghorbani, Mohsen Aminorroaya, Ashraf Amini, Masoud Int J Hypertens Research Article OBJECTIVE: To estimate the incidence of and risk factors for the development of hypertension (HTN) in people with T1D using routinely collected data. METHOD: The mean 16-year incidence of HTN was measured among 1,167 (557 men and 610 women) nonhypertensive patients with T1D from Isfahan Endocrine and Metabolism Research Center outpatient clinics, Iran. HTN was defined as a systolic blood pressure (BP) of 140 mm Hg or higher and/or a diastolic BP 90 mm Hg or higher and/or use of antihypertensive medications. The mean (standard deviation [SD]) age of participants was 20.6 years (10.5 years) with a mean (SD) duration of diabetes of 3.6 years (4.8 years) at registration. RESULTS: The prevalence of HTN at baseline was 9.7% (95% CI: 8.2, 11.5). Among the 1,167 patients free of HTN at registration who attended the clinic at least twice in the period 1992–2016, the incidence of HTN was 9.6 (8.0 women and 11.3 men) per 1000 person-years based on 18,870 person-years of follow-up. Multivariate analyses showed that male gender, older age, higher triglyceride, and higher systolic BP were significantly and independently associated with the development of HTN in this population. CONCLUSION: These findings will help the identification of those patients with T1D at particular risk of HTN and strongly support the case for vigorous control of BP in patients with T1D. Hindawi 2017 2017-12-20 /pmc/articles/PMC5750488/ /pubmed/29423321 http://dx.doi.org/10.1155/2017/3132729 Text en Copyright © 2017 Mohsen Janghorbani et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Janghorbani, Mohsen Aminorroaya, Ashraf Amini, Masoud Hypertension in Non-Type 2 Diabetes in Isfahan, Iran: Incidence and Risk Factors |
title | Hypertension in Non-Type 2 Diabetes in Isfahan, Iran: Incidence and Risk Factors |
title_full | Hypertension in Non-Type 2 Diabetes in Isfahan, Iran: Incidence and Risk Factors |
title_fullStr | Hypertension in Non-Type 2 Diabetes in Isfahan, Iran: Incidence and Risk Factors |
title_full_unstemmed | Hypertension in Non-Type 2 Diabetes in Isfahan, Iran: Incidence and Risk Factors |
title_short | Hypertension in Non-Type 2 Diabetes in Isfahan, Iran: Incidence and Risk Factors |
title_sort | hypertension in non-type 2 diabetes in isfahan, iran: incidence and risk factors |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750488/ https://www.ncbi.nlm.nih.gov/pubmed/29423321 http://dx.doi.org/10.1155/2017/3132729 |
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