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A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
This report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750514/ https://www.ncbi.nlm.nih.gov/pubmed/29423322 http://dx.doi.org/10.1155/2017/1050284 |
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author | Markland, Alison Hansen, Gregory Banks, Anke Chibbar, Rajni Adamko, Darryl |
author_facet | Markland, Alison Hansen, Gregory Banks, Anke Chibbar, Rajni Adamko, Darryl |
author_sort | Markland, Alison |
collection | PubMed |
description | This report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal replacement therapy (CRRT). This mechanism would have impacted recovery by removing factors such as endothelial microparticles, superantigens, and immune complexes that have been postulated as the pulmonary-renal link. This may be an interesting avenue of exploration going forward given the lack of evidence in treating such conditions and emergence of CRRT. |
format | Online Article Text |
id | pubmed-5750514 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-57505142018-02-08 A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis Markland, Alison Hansen, Gregory Banks, Anke Chibbar, Rajni Adamko, Darryl Case Rep Crit Care Case Report This report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal replacement therapy (CRRT). This mechanism would have impacted recovery by removing factors such as endothelial microparticles, superantigens, and immune complexes that have been postulated as the pulmonary-renal link. This may be an interesting avenue of exploration going forward given the lack of evidence in treating such conditions and emergence of CRRT. Hindawi 2017 2017-12-20 /pmc/articles/PMC5750514/ /pubmed/29423322 http://dx.doi.org/10.1155/2017/1050284 Text en Copyright © 2017 Alison Markland et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Markland, Alison Hansen, Gregory Banks, Anke Chibbar, Rajni Adamko, Darryl A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis |
title | A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis |
title_full | A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis |
title_fullStr | A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis |
title_full_unstemmed | A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis |
title_short | A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis |
title_sort | pediatric case of diffuse alveolar hemorrhage secondary to poststreptococcal glomerulonephritis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750514/ https://www.ncbi.nlm.nih.gov/pubmed/29423322 http://dx.doi.org/10.1155/2017/1050284 |
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