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A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis

This report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal...

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Detalles Bibliográficos
Autores principales: Markland, Alison, Hansen, Gregory, Banks, Anke, Chibbar, Rajni, Adamko, Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750514/
https://www.ncbi.nlm.nih.gov/pubmed/29423322
http://dx.doi.org/10.1155/2017/1050284
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author Markland, Alison
Hansen, Gregory
Banks, Anke
Chibbar, Rajni
Adamko, Darryl
author_facet Markland, Alison
Hansen, Gregory
Banks, Anke
Chibbar, Rajni
Adamko, Darryl
author_sort Markland, Alison
collection PubMed
description This report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal replacement therapy (CRRT). This mechanism would have impacted recovery by removing factors such as endothelial microparticles, superantigens, and immune complexes that have been postulated as the pulmonary-renal link. This may be an interesting avenue of exploration going forward given the lack of evidence in treating such conditions and emergence of CRRT.
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spelling pubmed-57505142018-02-08 A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis Markland, Alison Hansen, Gregory Banks, Anke Chibbar, Rajni Adamko, Darryl Case Rep Crit Care Case Report This report summarizes a case of a 4-year-old girl with poststreptococcal glomerulonephritis and diffuse alveolar hemorrhage, an atypical presentation in this age group and type of vasculitic disease. We propose that her rapid improvement in clinical status was due to her treatment, continuous renal replacement therapy (CRRT). This mechanism would have impacted recovery by removing factors such as endothelial microparticles, superantigens, and immune complexes that have been postulated as the pulmonary-renal link. This may be an interesting avenue of exploration going forward given the lack of evidence in treating such conditions and emergence of CRRT. Hindawi 2017 2017-12-20 /pmc/articles/PMC5750514/ /pubmed/29423322 http://dx.doi.org/10.1155/2017/1050284 Text en Copyright © 2017 Alison Markland et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Markland, Alison
Hansen, Gregory
Banks, Anke
Chibbar, Rajni
Adamko, Darryl
A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_full A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_fullStr A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_full_unstemmed A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_short A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis
title_sort pediatric case of diffuse alveolar hemorrhage secondary to poststreptococcal glomerulonephritis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750514/
https://www.ncbi.nlm.nih.gov/pubmed/29423322
http://dx.doi.org/10.1155/2017/1050284
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