Altered Protein Expression of Cardiac CYP2J and Hepatic CYP2C, CYP4A, and CYP4F in a Mouse Model of Type II Diabetes—A Link in the Onset and Development of Cardiovascular Disease?

Arachidonic acid can be metabolized by cytochrome P450 (CYP450) enzymes in a tissue- and cell-specific manner to generate vasoactive products such as epoxyeicosatrienoic acids (EETs-cardioprotective) and hydroxyeicosatetraenoic acids (HETEs-cardiotoxic). Type II diabetes is a well-recognized risk fa...

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Detalles Bibliográficos
Autores principales: Drolet, Benoit, Pilote, Sylvie, Gélinas, Carolanne, Kamaliza, Alida-Douce, Blais-Boilard, Audrey, Virgili, Jessica, Patoine, Dany, Simard, Chantale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750650/
https://www.ncbi.nlm.nih.gov/pubmed/29023376
http://dx.doi.org/10.3390/pharmaceutics9040044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750650/
https://www.ncbi.nlm.nih.gov/pubmed/29023376
http://dx.doi.org/10.3390/pharmaceutics9040044

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