Cargando…

Application of Pharmacokinetics Modelling to Predict Human Exposure of a Cationic Liposomal Subunit Antigen Vaccine System

The pharmacokinetics of a liposomal subunit antigen vaccine system composed of the cationic lipid dimethyldioctadecylammonium bromide (DDA) and the immunostimulatory agent trehalose 6,6-dibehenate (TDB) (8:1 molar ratio) combined with the Ag85B-ESAT-6 (H1) antigen were modelled using mouse in-vivo d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Badhan, Raj K. S., Khadke, Swapnil, Perrie, Yvonne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750663/ https://www.ncbi.nlm.nih.gov/pubmed/29215597 http://dx.doi.org/10.3390/pharmaceutics9040057

Ejemplares similares

Point of use production of liposomal solubilised products
por: Khadke, Swapnil, et al.
Publicado: (2018)

Radiolabelling of Antigen and Liposomes for Vaccine Biodistribution Studies
por: Henriksen-Lacey, Malou, et al.
Publicado: (2010)

The Impact of Solvent Selection: Strategies to Guide the Manufacturing of Liposomes Using Microfluidics
por: Webb, Cameron, et al.
Publicado: (2019)

Applying Microfluidics for the Production of the Cationic Liposome-Based Vaccine Adjuvant CAF09b
por: Schmidt, Signe Tandrup, et al.
Publicado: (2020)

The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile
por: Schmidt, Signe Tandrup, et al.
Publicado: (2016)

Adjuvant Effect of Cationic Liposomes for Subunit Influenza Vaccine: Influence of Antigen Loading Method, Cholesterol and Immune Modulators
por: Barnier-Quer, Christophe, et al.
Publicado: (2013)

Synthesis of protein conjugates adsorbed on cationic liposomes surface
por: Chatzikleanthous, Despo, et al.
Publicado: (2020)

Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
por: Tandrup Schmidt, Signe, et al.
Publicado: (2016)

Small Cationic DDA:TDB Liposomes as Protein Vaccine Adjuvants Obviate the Need for TLR Agonists in Inducing Cellular and Humoral Responses
por: Milicic, Anita, et al.
Publicado: (2012)

Immunomic Discovery of Adjuvants, Delivery Systems, and Candidate Subunit Vaccines: A Brief Introduction
por: Flower, Darren R., et al.
Publicado: (2012)

Cationic Liposomes: A Flexible Vaccine Delivery System for Physicochemically Diverse Antigenic Peptides
por: Heuts, Jeroen, et al.
Publicado: (2018)

Optimising Fluvoxamine Maternal/Fetal Exposure during Gestation: A Pharmacokinetic Virtual Clinical Trials Study
por: Burhanuddin, Khairulanwar, et al.
Publicado: (2022)

Development of a Region-Specific Physiologically Based Pharmacokinetic Brain Model to Assess Hippocampus and Frontal Cortex Pharmacokinetics
por: Zakaria, Zaril, et al.
Publicado: (2018)

Preparation, characterization, and efficient transfection of cationic liposomes and nanomagnetic cationic liposomes
por: Samadikhah, Hamid Reza, et al.
Publicado: (2011)

Cationic Liposome Conjugation to Recombinant Adenoviral Vector Reduces Viral Antigenicity
por: Natsume, Atsushi, et al.
Publicado: (2000)

Preparation of Zein-Based Nanoparticles: Nanoprecipitation versus Microfluidic-Assisted Manufacture, Effects of PEGylation on Nanoparticle Characteristics and Cellular Uptake by Melanoma Cells
por: Meewan, Jitkasem, et al.
Publicado: (2022)

Comparison of BCG, MPL and cationic liposome adjuvant systems in leishmanial antigen vaccine formulations against murine visceral leishmaniasis
por: Ravindran, Rajesh, et al.
Publicado: (2010)

Comparative Analysis of Protein Quantification Methods for the Rapid Determination of Protein Loading in Liposomal Formulations
por: Hussain, Maryam T., et al.
Publicado: (2019)

Pharmacokinetics, Tissue Distribution and Therapeutic Effect of Cationic Thermosensitive Liposomal Doxorubicin Upon Mild Hyperthermia
por: Dicheva, Bilyana M., et al.
Publicado: (2015)

Development of a Physiologically-Based Pharmacokinetic Model of the Rat Central Nervous System
por: Badhan, Raj K. Singh, et al.
Publicado: (2014)

Rapid Quantification and Validation of Lipid Concentrations within Liposomes
por: Roces, Carla B., et al.
Publicado: (2016)

Licensed liposomal vaccines and adjuvants in the antigen delivery system
por: Krasnopolsky, Yuriy, et al.
Publicado: (2022)

Role of interleukin-6 in antigen-specific mucosal immunoglobulin A induction by cationic liposomes
por: Tada, Rui, et al.
Publicado: (2021)

Formation and purification of tailored liposomes for drug delivery using a module-based micro continuous-flow system
por: Dimov, Nikolay, et al.
Publicado: (2017)

Cationic liposomes promote antigen cross-presentation in dendritic cells by alkalizing the lysosomal pH and limiting the degradation of antigens
por: Gao, Jie, et al.
Publicado: (2017)

VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines
por: Doytchinova, Irini A, et al.
Publicado: (2007)

Hepatic toxicity assessment of cationic liposome exposure in healthy and chronic alcohol fed mice
por: Kermanizadeh, Ali, et al.
Publicado: (2017)

Combining Cationic Liposomal Delivery with MPL-TDM for Cysteine Protease Cocktail Vaccination against Leishmania donovani : Evidence for Antigen Synergy and Protection
por: Das, Amrita, et al.
Publicado: (2014)

Clopidogrel Pharmacokinetics in Malaysian Population Groups: The Impact of Inter-Ethnic Variability
por: Zakaria, Zaril H., et al.
Publicado: (2018)

Author Correction: Formation and purification of tailored liposomes for drug delivery using a module-based micro continuous-flow system
por: Dimov, Nikolay, et al.
Publicado: (2018)

Application of Pharmacokinetic and Pharmacodynamic Analysis to the Development of Liposomal Formulations for Oncology
por: Ait-Oudhia, Sihem, et al.
Publicado: (2014)

Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems
por: Feather, Laura A. J., et al.
Publicado: (2022)

Preparation and Characterization of New Liposomes. Bactericidal Activity of Cefepime Encapsulated into Cationic Liposomes
por: Moyá, Maria Luisa, et al.
Publicado: (2019)

Redirecting adenovirus to pulmonary endothelium by cationic liposomes
por: Ma, Z, et al.
Publicado: (2002)

Correction: Combining Cationic Liposomal Delivery with MPL-TDM for Cysteine Protease Cocktail Vaccination against Leishmania donovani: Evidence for Antigen Synergy and Protection
por: Das, Amrita, et al.
Publicado: (2015)

Design Variation of a Dual-Antigen Liposomal Vaccine Carrier System
por: Nayerhoda, Roozbeh, et al.
Publicado: (2019)

DNA-Loaded Cationic Liposomes Efficiently Function as a Vaccine against Malarial Proteins
por: Fotoran, Wesley L., et al.
Publicado: (2017)

Anti-RSV Peptide-Loaded Liposomes for the Inhibition of Respiratory Syncytial Virus †
por: Joshi, Sameer, et al.
Publicado: (2018)

Pharmacokinetic Analyses of Liposomal and Non-Liposomal Multivitamin/Mineral Formulations
por: Ko, Joungbo, et al.
Publicado: (2023)

Choroidal neovascularization reduced by targeted drug delivery with cationic liposome-encapsulated paclitaxel or targeted photodynamic therapy with verteporfin encapsulated in cationic liposomes
por: Gross, Nikolai, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_tg41ib7gmbma1pt41a2sg7fc2o