Coxiella burnetii Lipopolysaccharide: What Do We Know?

A small gram-negative bacterium, Coxiella burnetii (C. burnetii), is responsible for a zoonosis called Q fever. C. burnetii is an intracellular bacterium that can survive inside microbicidal cells like monocytes and macrophages by hijacking several functions of the immune system. Among several virul...

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Detalles Bibliográficos
Autores principales: Abnave, Prasad, Muracciole, Xavier, Ghigo, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751112/
https://www.ncbi.nlm.nih.gov/pubmed/29168790
http://dx.doi.org/10.3390/ijms18122509
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author Abnave, Prasad
Muracciole, Xavier
Ghigo, Eric
author_facet Abnave, Prasad
Muracciole, Xavier
Ghigo, Eric
author_sort Abnave, Prasad
collection PubMed
description A small gram-negative bacterium, Coxiella burnetii (C. burnetii), is responsible for a zoonosis called Q fever. C. burnetii is an intracellular bacterium that can survive inside microbicidal cells like monocytes and macrophages by hijacking several functions of the immune system. Among several virulence factors, the lipopolysaccharide (LPS) of C. burnetii is one of the major factors involved in this immune hijacking because of its atypical composition and structure. Thus, the aim of this mini-review is to summarize the repressive effects of C. burnetii LPS on the antibacterial immunity of cells.
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spelling pubmed-57511122018-01-08 Coxiella burnetii Lipopolysaccharide: What Do We Know? Abnave, Prasad Muracciole, Xavier Ghigo, Eric Int J Mol Sci Review A small gram-negative bacterium, Coxiella burnetii (C. burnetii), is responsible for a zoonosis called Q fever. C. burnetii is an intracellular bacterium that can survive inside microbicidal cells like monocytes and macrophages by hijacking several functions of the immune system. Among several virulence factors, the lipopolysaccharide (LPS) of C. burnetii is one of the major factors involved in this immune hijacking because of its atypical composition and structure. Thus, the aim of this mini-review is to summarize the repressive effects of C. burnetii LPS on the antibacterial immunity of cells. MDPI 2017-11-23 /pmc/articles/PMC5751112/ /pubmed/29168790 http://dx.doi.org/10.3390/ijms18122509 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Abnave, Prasad
Muracciole, Xavier
Ghigo, Eric
Coxiella burnetii Lipopolysaccharide: What Do We Know?
title Coxiella burnetii Lipopolysaccharide: What Do We Know?
title_full Coxiella burnetii Lipopolysaccharide: What Do We Know?
title_fullStr Coxiella burnetii Lipopolysaccharide: What Do We Know?
title_full_unstemmed Coxiella burnetii Lipopolysaccharide: What Do We Know?
title_short Coxiella burnetii Lipopolysaccharide: What Do We Know?
title_sort coxiella burnetii lipopolysaccharide: what do we know?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751112/
https://www.ncbi.nlm.nih.gov/pubmed/29168790
http://dx.doi.org/10.3390/ijms18122509
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