Cargando…

Regulation of the Tumor-Suppressor BECLIN 1 by Distinct Ubiquitination Cascades

Autophagy contributes to cellular homeostasis through the degradation of various intracellular targets such as proteins, organelles and microbes. This relates autophagy to various diseases such as infections, neurodegenerative diseases and cancer. A central component of the autophagy machinery is th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boutouja, Fahd, Brinkmeier, Rebecca, Mastalski, Thomas, El Magraoui, Fouzi, Platta, Harald W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751144/ https://www.ncbi.nlm.nih.gov/pubmed/29186924 http://dx.doi.org/10.3390/ijms18122541

Ejemplares similares

Vps10-mediated targeting of Pep4 determines the activity of the vacuole in a substrate-dependent manner
por: Boutouja, Fahd, et al.
Publicado: (2019)

Vac8 Controls Vacuolar Membrane Dynamics during Different Autophagy Pathways in Saccharomyces cerevisiae
por: Boutouja, Fahd, et al.
Publicado: (2019)

Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO
por: Reidick, Christina, et al.
Publicado: (2014)

The Cytosolic Domain of Pex22p Stimulates the Pex4p-Dependent Ubiquitination of the PTS1-Receptor
por: El Magraoui, Fouzi, et al.
Publicado: (2014)

The Peroxisomal PTS1-Import Defect of PEX1- Deficient Cells Is Independent of Pexophagy in Saccharomyces cerevisiae
por: Mastalski, Thomas, et al.
Publicado: (2020)

Ubiquitination of the peroxisomal import receptor Pex5p is required for its recycling
por: Platta, Harald W., et al.
Publicado: (2007)

Autophagy Stimulus-Dependent Role of the Small GTPase Ras2 in Peroxisome Degradation
por: Boutouja, Fahd, et al.
Publicado: (2020)

mTOR: A Cellular Regulator Interface in Health and Disease
por: Boutouja, Fahd, et al.
Publicado: (2019)

Autophagy-Related Deubiquitinating Enzymes Involved in Health and Disease
por: El Magraoui, Fouzi, et al.
Publicado: (2015)

Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
por: Platta, Harald W., et al.
Publicado: (2011)

USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1
por: Xu, Daichao, et al.
Publicado: (2016)

IL-17B/IL-17RB signaling cascade contributes to self-renewal and tumorigenesis of cancer stem cells by regulating Beclin-1 ubiquitination
por: Bie, Qingli, et al.
Publicado: (2021)

Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin
por: Wijshake, Tobias, et al.
Publicado: (2021)

The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System
por: Armstrong, Stephen R., et al.
Publicado: (2016)

Cysteine-specific ubiquitination protects the peroxisomal import receptor Pex5p against proteasomal degradation
por: Schwartzkopff, Benjamin, et al.
Publicado: (2015)

Competitive ubiquitination activates the tumor suppressor p53
por: Li, Xingyao, et al.
Publicado: (2019)

Development of inhibitors in the ubiquitination cascade
por: Zhang, Wei, et al.
Publicado: (2014)

Targeting the Ubiquitin Signaling Cascade in Tumor Microenvironment for Cancer Therapy
por: Liu, Qi, et al.
Publicado: (2021)

Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN
por: Hsu, Wei-Lun, et al.
Publicado: (2023)

Beclin 1 Phosphorylation – at the Center of Autophagy Regulation
por: Menon, Manoj B., et al.
Publicado: (2018)

BECLIN1: Protein Structure, Function and Regulation
por: Tran, Sharon, et al.
Publicado: (2021)

Polyglutamine tracts regulate beclin 1-dependent autophagy
por: Ashkenazi, Avraham, et al.
Publicado: (2017)

A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas
por: Cervia, Lisa D., et al.
Publicado: (2023)

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction
por: Decuypere, Jean-Paul, et al.
Publicado: (2012)

Ubiquitin-Specific Protease 14 Negatively Regulates Toll-Like Receptor 4-Mediated Signaling and Autophagy Induction by Inhibiting Ubiquitination of TAK1-Binding Protein 2 and Beclin 1
por: Min, Yoon, et al.
Publicado: (2017)

Ubiquitin Specific Peptidase 22 Regulates Histone H2B Mono-Ubiquitination and Exhibits Both Oncogenic and Tumor Suppressor Roles in Cancer
por: Jeusset, Lucile M-P., et al.
Publicado: (2017)

The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma
por: Morgado-Palacin, Lucia, et al.
Publicado: (2023)

SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection
por: Gassen, Nils C., et al.
Publicado: (2019)

SCF(β-TRCP) E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation
por: Ci, Yanpeng, et al.
Publicado: (2018)

Several Distinct Polycomb Complexes Regulate and Co-Localize on the INK4a Tumor Suppressor Locus
por: Maertens, Goedele N., et al.
Publicado: (2009)

Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia
por: Koukourakis, M I, et al.
Publicado: (2010)

Regulation of Amyloid Precursor Protein Processing by the Beclin 1 Complex
por: Jaeger, Philipp A., et al.
Publicado: (2010)

The VMP1-Beclin 1 interaction regulates autophagy induction
por: Molejon, Maria I., et al.
Publicado: (2013)

Regulation of Beclin 1-Mediated Autophagy by Oncogenic Tyrosine Kinases
por: Vega-Rubín-de-Celis, Silvia, et al.
Publicado: (2020)

KF-1 Ubiquitin Ligase: An Anxiety Suppressor
por: Hashimoto-Gotoh, Tamotsu, et al.
Publicado: (2009)

CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer
por: Lee, Yu-Ju, et al.
Publicado: (2019)

A Tumor-Associated Mutation of FYVE-CENT Prevents Its Interaction with Beclin 1 and Interferes with Cytokinesis
por: Sagona, Antonia P., et al.
Publicado: (2011)

Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor
por: Maertens, Goedele N, et al.
Publicado: (2010)

Metabolic mechanisms regulating distinct steps of the melanoma metastatic cascade
por: Piskounova, Elena, et al.
Publicado: (2014)

Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors
por: Li, Zidong, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_1ppc293h0due98ojsgnfkeimtk