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The E3 Ubiquitin Ligase RNF7 Negatively Regulates CARD14/CARMA2sh Signaling

The three CARD-containing MAGUK (CARMA) proteins function as scaffolding molecules that regulate activation of the pro-inflammatory transcription factor NF-κB. Recently, mutations in CARMA2 have been linked to psoriasis susceptibility due to their acquired altered capacity to activate NF-κB. By mean...

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Detalles Bibliográficos
Autores principales:	Telesio, Gianluca, Scudiero, Ivan, Pizzulo, Maddalena, Mazzone, Pellegrino, Zotti, Tiziana, Voccola, Serena, Polvere, Immacolata, Vito, Pasquale, Stilo, Romania
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751184/ https://www.ncbi.nlm.nih.gov/pubmed/29194363 http://dx.doi.org/10.3390/ijms18122581

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