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l-Glutamine Attenuates Apoptosis Induced by Endoplasmic Reticulum Stress by Activating the IRE1α-XBP1 Axis in IPEC-J2: A Novel Mechanism of l-Glutamine in Promoting Intestinal Health

Intestinal absorption and barrier malfunctions are associated with endoplasmic reticulum stress (ERS) in the intestine. We induced ERS by exposing the intestinal porcine epithelial cell line J2 (IPEC-J2) to tunicamycin (TUNI) to explore the potential of l-glutamine to reduce ERS-induced apoptosis. O...

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Detalles Bibliográficos
Autores principales: Jiang, Qian, Chen, Jiashun, Liu, Shaojuan, Liu, Gang, Yao, Kang, Yin, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751220/
https://www.ncbi.nlm.nih.gov/pubmed/29206200
http://dx.doi.org/10.3390/ijms18122617