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Cut-Off Values of Hematologic Parameters to Predict the Number of Alpha Genes Deleted in Subjects with Deletional Alpha Thalassemia

Most α-thalassemia cases are caused by deletions of the structural α-globin genes. The degree of microcytosis and hypochromia has been correlated with the number of affected α-globin genes, suggesting a promising role of hematologic parameters as predictive diagnostic tools. However, cut-off points...

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Detalles Bibliográficos
Autores principales: Velasco-Rodríguez, Diego, Blas, Carlos, Alonso-Domínguez, Juan-Manuel, Vega, Gala, Soto, Carlos, García-Raso, Aránzazu, Llamas-Sillero, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751308/
https://www.ncbi.nlm.nih.gov/pubmed/29236053
http://dx.doi.org/10.3390/ijms18122707