Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice

We generated myeloid specific sphingosine-1-phosphate receptor 1 (S1pr1) deficient mice by crossing mice that had myeloid specific expression of Cre recombinase (lyzM(Cre)) with mice having the S1pr1 gene flanked by loxP recombination sites. We transplanted bone marrow from these mice and control ly...

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Detalles Bibliográficos
Autores principales: Gonzalez, Leticia, Qian, Alexander S., Tahir, Usama, Yu, Pei, Trigatti, Bernardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751322/
https://www.ncbi.nlm.nih.gov/pubmed/29244772
http://dx.doi.org/10.3390/ijms18122721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751322/
https://www.ncbi.nlm.nih.gov/pubmed/29244772
http://dx.doi.org/10.3390/ijms18122721

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