Cargando…

Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice

We generated myeloid specific sphingosine-1-phosphate receptor 1 (S1pr1) deficient mice by crossing mice that had myeloid specific expression of Cre recombinase (lyzM(Cre)) with mice having the S1pr1 gene flanked by loxP recombination sites. We transplanted bone marrow from these mice and control ly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gonzalez, Leticia, Qian, Alexander S., Tahir, Usama, Yu, Pei, Trigatti, Bernardo L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751322/ https://www.ncbi.nlm.nih.gov/pubmed/29244772 http://dx.doi.org/10.3390/ijms18122721

Ejemplares similares

High Density Lipoprotein Stimulated Migration of Macrophages Depends on the Scavenger Receptor Class B, Type I, PDZK1 and Akt1 and Is Blocked by Sphingosine 1 Phosphate Receptor Antagonists
por: Al-Jarallah, Aishah, et al.
Publicado: (2014)

Sphingosine 1-Phosphate and Atherosclerosis
por: Kurano, Makoto, et al.
Publicado: (2018)

CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice
por: Riopel, Matthew, et al.
Publicado: (2018)

Data on leukocyte PDZK1 deficiency affecting macrophage apoptosis but not monocyte recruitment, cell proliferation, macrophage abundance or ER stress in atherosclerotic plaques of LDLR deficient mice
por: Yu, Pei, et al.
Publicado: (2018)

PAR4 Inhibition Reduces Coronary Artery Atherosclerosis and Myocardial Fibrosis in SR-B1/LDLR Double Knockout Mice
por: Lee, Samuel K., et al.
Publicado: (2023)

Sphingolipids and Atherosclerosis: The Dual Role of Ceramide and Sphingosine-1-Phosphate
por: Piccoli, Marco, et al.
Publicado: (2023)

AAV2/8-humanFOXP3 gene therapy shows robust anti-atherosclerosis efficacy in LDLR-KO mice on high cholesterol diet
por: Cao, M, et al.
Publicado: (2015)

Interaction of microRNAs with sphingosine kinases, sphingosine-1 phosphate, and sphingosine-1 phosphate receptors in cancer
por: Xu, Guangmeng, et al.
Publicado: (2021)

Sphingosine-1-phosphate signaling in Leishmania donovani infection in macrophages
por: Arish, Mohd, et al.
Publicado: (2018)

The Role of Sphingolipids and Sphingosine-1-phosphate—Sphingosine-1-phosphate-receptor Signaling in Psoriasis
por: Masuda-Kuroki, Kana, et al.
Publicado: (2023)

Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice
por: Babaev, Vladimir R., et al.
Publicado: (2014)

Tanshinone IIA alleviates atherosclerosis in LDLR(−/−) mice by regulating efferocytosis of macrophages
por: Wang, Jiarou, et al.
Publicado: (2023)

Sphingosine Kinase 1 and Sphingosine-1-Phosphate Signaling in Colorectal Cancer
por: Bao, Yonghua, et al.
Publicado: (2017)

Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer’s disease
por: Ceccom, Johnatan, et al.
Publicado: (2014)

Sphingosine-1-Phosphate-Specific G Protein-Coupled Receptors as Novel Therapeutic Targets for Atherosclerosis
por: Okamoto, Yasuo, et al.
Publicado: (2011)

CD36/SR-B2-TLR2 Dependent Pathways Enhance Porphyromonas gingivalis Mediated Atherosclerosis in the Ldlr KO Mouse Model
por: Brown, Paul M., et al.
Publicado: (2015)

T Cells in Atherosclerosis in Ldlr−/− and Apoe−/− Mice
por: Getz, Godfrey S., et al.
Publicado: (2018)

Sphingosine-1-Phosphate and Macrophage Biology—How the Sphinx Tames the Big Eater
por: Weigert, Andreas, et al.
Publicado: (2019)

Interesterified Fats Induce Deleterious Effects on Adipose Tissue and Liver in LDLr-KO Mice
por: Lavrador, Maria Silvia Ferrari, et al.
Publicado: (2019)

Sphingosine‐1‐phosphate improves outcome of no‐reflow acute myocardial infarction via sphingosine‐1‐phosphate receptor 1
por: Polzin, Amin, et al.
Publicado: (2022)

Dihydro-sphingosine 1-phosphate interacts with carrier proteins in a manner distinct from that of sphingosine 1-phosphate
por: Mishima, Yuko, et al.
Publicado: (2018)

Irisin Is Target of Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor-Mediated Signaling in Skeletal Muscle Cells
por: Pierucci, Federica, et al.
Publicado: (2023)

Commentary: The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension
por: Bhavanam, Naga P., et al.
Publicado: (2015)

Impairment of Angiogenic Sphingosine Kinase-1/Sphingosine-1-Phosphate Receptors Pathway in Preeclampsia
por: Dobierzewska, Aneta, et al.
Publicado: (2016)

Implication of Ceramide, Ceramide 1-Phosphate and Sphingosine 1-Phosphate in Tumorigenesis
por: Gangoiti, Patricia, et al.
Publicado: (2008)

The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer
por: Hait, Nitai C., et al.
Publicado: (2017)

Dual AAV/IL-10 Plus STAT3 Anti-Inflammatory Gene Delivery Lowers Atherosclerosis in LDLR KO Mice, but without Increased Benefit
por: Cao, Maohua, et al.
Publicado: (2012)

Correction: CD36/SR-B2-TLR2 Dependent Pathways Enhance Porphyromonas gingivalis Mediated Atherosclerosis in the Ldlr KO Mouse Model
Publicado: (2015)

Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3
por: Li, Chao, et al.
Publicado: (2015)

The Apolipoprotein M–Sphingosine-1-Phosphate Axis: Biological Relevance in Lipoprotein Metabolism, Lipid Disorders and Atherosclerosis
por: Arkensteijn, Bas W. C., et al.
Publicado: (2013)

Hepatocyte-Derived Lipotoxic Extracellular Vesicle Sphingosine 1-Phosphate Induces Macrophage Chemotaxis
por: Liao, Chieh-Yu, et al.
Publicado: (2018)

Sphingosine Kinases/Sphingosine-1-Phosphate and Death Signalling in APP-Transfected Cells
por: Gassowska, Magdalena, et al.
Publicado: (2014)

Characterizing Sphingosine Kinases and Sphingosine 1-Phosphate Receptors in the Mammalian Eye and Retina
por: Porter, Hunter, et al.
Publicado: (2018)

Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System
por: Cannavo, Alessandro, et al.
Publicado: (2017)

Targeting sphingosine-1-phosphate for cancer therapy
por: Sabbadini, R A
Publicado: (2006)

Immunological Function of Sphingosine 1-Phosphate in the Intestine
por: Kunisawa, Jun, et al.
Publicado: (2012)

Plasma Sphingosine-1-Phosphate Is Elevated in Obesity
por: Kowalski, Greg M., et al.
Publicado: (2013)

Sphingosine 1-Phosphate in Acute Dengue Infection
por: Gomes, Laksiri, et al.
Publicado: (2014)

Sphingosine 1-Phosphate signaling controls mitosis
por: Cuvillier, Olivier, et al.
Publicado: (2017)

Roles of sphingosine-1-phosphate signaling in cancer
por: Wang, Peng, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7os5kd9v1lg0prpu10hf354pa7