Control of Nucleotide Metabolism Enables Mutant p53’s Oncogenic Gain-of-Function Activity

Since its discovery as an oncoprotein in 1979, investigation into p53’s many identities has completed a full circle and today it is inarguably the most extensively studied tumor suppressor (wild-type p53 form or WTp53) and oncogene (mutant p53 form or mtp53) in cancer research. After the p53 protein...

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Detalles Bibliográficos
Autores principales: Schmidt, Valentina, Nagar, Rachana, Martinez, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751358/
https://www.ncbi.nlm.nih.gov/pubmed/29257071
http://dx.doi.org/10.3390/ijms18122759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751358/
https://www.ncbi.nlm.nih.gov/pubmed/29257071
http://dx.doi.org/10.3390/ijms18122759

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