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Control of Nucleotide Metabolism Enables Mutant p53’s Oncogenic Gain-of-Function Activity
Since its discovery as an oncoprotein in 1979, investigation into p53’s many identities has completed a full circle and today it is inarguably the most extensively studied tumor suppressor (wild-type p53 form or WTp53) and oncogene (mutant p53 form or mtp53) in cancer research. After the p53 protein...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751358/ https://www.ncbi.nlm.nih.gov/pubmed/29257071 http://dx.doi.org/10.3390/ijms18122759 |