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Lym-1 Chimeric Antigen Receptor T Cells Exhibit Potent Anti-Tumor Effects against B-Cell Lymphoma

T cells expressing chimeric antigen receptors (CARs) recognizing CD19 epitopes have produced remarkable anti-tumor effects in patients with B-cell malignancies. However, cancer cells lacking recognized epitopes can emerge, leading to relapse and death. Thus, CAR T cells targeting different epitopes...

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Detalles Bibliográficos
Autores principales: Zheng, Long, Hu, Peisheng, Wolfe, Brandon, Gonsalves, Caryn, Ren, Luqing, Khawli, Leslie A., Kaslow, Harvey R., Epstein, Alan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751371/
https://www.ncbi.nlm.nih.gov/pubmed/29261129
http://dx.doi.org/10.3390/ijms18122773

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