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A multiple distributed representation method based on neural network for biomedical event extraction
BACKGROUND: Biomedical event extraction is one of the most frontier domains in biomedical research. The two main subtasks of biomedical event extraction are trigger identification and arguments detection which can both be considered as classification problems. However, traditional state-of-the-art m...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751641/ https://www.ncbi.nlm.nih.gov/pubmed/29297321 http://dx.doi.org/10.1186/s12911-017-0563-9 |
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author | Wang, Anran Wang, Jian Lin, Hongfei Zhang, Jianhai Yang, Zhihao Xu, Kan |
author_facet | Wang, Anran Wang, Jian Lin, Hongfei Zhang, Jianhai Yang, Zhihao Xu, Kan |
author_sort | Wang, Anran |
collection | PubMed |
description | BACKGROUND: Biomedical event extraction is one of the most frontier domains in biomedical research. The two main subtasks of biomedical event extraction are trigger identification and arguments detection which can both be considered as classification problems. However, traditional state-of-the-art methods are based on support vector machine (SVM) with massive manually designed one-hot represented features, which require enormous work but lack semantic relation among words. METHODS: In this paper, we propose a multiple distributed representation method for biomedical event extraction. The method combines context consisting of dependency-based word embedding, and task-based features represented in a distributed way as the input of deep learning models to train deep learning models. Finally, we used softmax classifier to label the example candidates. RESULTS: The experimental results on Multi-Level Event Extraction (MLEE) corpus show higher F-scores of 77.97% in trigger identification and 58.31% in overall compared to the state-of-the-art SVM method. CONCLUSIONS: Our distributed representation method for biomedical event extraction avoids the problems of semantic gap and dimension disaster from traditional one-hot representation methods. The promising results demonstrate that our proposed method is effective for biomedical event extraction. |
format | Online Article Text |
id | pubmed-5751641 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-57516412018-01-05 A multiple distributed representation method based on neural network for biomedical event extraction Wang, Anran Wang, Jian Lin, Hongfei Zhang, Jianhai Yang, Zhihao Xu, Kan BMC Med Inform Decis Mak Research BACKGROUND: Biomedical event extraction is one of the most frontier domains in biomedical research. The two main subtasks of biomedical event extraction are trigger identification and arguments detection which can both be considered as classification problems. However, traditional state-of-the-art methods are based on support vector machine (SVM) with massive manually designed one-hot represented features, which require enormous work but lack semantic relation among words. METHODS: In this paper, we propose a multiple distributed representation method for biomedical event extraction. The method combines context consisting of dependency-based word embedding, and task-based features represented in a distributed way as the input of deep learning models to train deep learning models. Finally, we used softmax classifier to label the example candidates. RESULTS: The experimental results on Multi-Level Event Extraction (MLEE) corpus show higher F-scores of 77.97% in trigger identification and 58.31% in overall compared to the state-of-the-art SVM method. CONCLUSIONS: Our distributed representation method for biomedical event extraction avoids the problems of semantic gap and dimension disaster from traditional one-hot representation methods. The promising results demonstrate that our proposed method is effective for biomedical event extraction. BioMed Central 2017-12-20 /pmc/articles/PMC5751641/ /pubmed/29297321 http://dx.doi.org/10.1186/s12911-017-0563-9 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Wang, Anran Wang, Jian Lin, Hongfei Zhang, Jianhai Yang, Zhihao Xu, Kan A multiple distributed representation method based on neural network for biomedical event extraction |
title | A multiple distributed representation method based on neural network for biomedical event extraction |
title_full | A multiple distributed representation method based on neural network for biomedical event extraction |
title_fullStr | A multiple distributed representation method based on neural network for biomedical event extraction |
title_full_unstemmed | A multiple distributed representation method based on neural network for biomedical event extraction |
title_short | A multiple distributed representation method based on neural network for biomedical event extraction |
title_sort | multiple distributed representation method based on neural network for biomedical event extraction |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751641/ https://www.ncbi.nlm.nih.gov/pubmed/29297321 http://dx.doi.org/10.1186/s12911-017-0563-9 |
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