Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering

We used surface-enhanced Raman scattering (SERS) for the quantitative and sensitive detection of chloramphenicol (CAP). Using 30 nm colloidal Au nanoparticles (NPs), a low detection limit for CAP of 10(−8) M was obtained. The characteristic Raman peak of CAP centered at 1344 cm(−1) was used for the...

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Autores principales: Ding, Yufeng, Zhang, Xin, Yin, Hongjun, Meng, Qingyun, Zhao, Yongmei, Liu, Luo, Wu, Zhenglong, Xu, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751667/
https://www.ncbi.nlm.nih.gov/pubmed/29261161
http://dx.doi.org/10.3390/s17122962
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author Ding, Yufeng
Zhang, Xin
Yin, Hongjun
Meng, Qingyun
Zhao, Yongmei
Liu, Luo
Wu, Zhenglong
Xu, Haijun
author_facet Ding, Yufeng
Zhang, Xin
Yin, Hongjun
Meng, Qingyun
Zhao, Yongmei
Liu, Luo
Wu, Zhenglong
Xu, Haijun
author_sort Ding, Yufeng
collection PubMed
description We used surface-enhanced Raman scattering (SERS) for the quantitative and sensitive detection of chloramphenicol (CAP). Using 30 nm colloidal Au nanoparticles (NPs), a low detection limit for CAP of 10(−8) M was obtained. The characteristic Raman peak of CAP centered at 1344 cm(−1) was used for the rapid quantitative detection of CAP in three different types of CAP eye drops, and the accuracy of the measurement result was verified by high-performance liquid chromatography (HPLC). The experimental results reveal that the SERS technique based on colloidal Au NPs is accurate and sensitive, and can be used for the rapid detection of various antibiotics.
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spelling pubmed-57516672018-01-10 Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering Ding, Yufeng Zhang, Xin Yin, Hongjun Meng, Qingyun Zhao, Yongmei Liu, Luo Wu, Zhenglong Xu, Haijun Sensors (Basel) Article We used surface-enhanced Raman scattering (SERS) for the quantitative and sensitive detection of chloramphenicol (CAP). Using 30 nm colloidal Au nanoparticles (NPs), a low detection limit for CAP of 10(−8) M was obtained. The characteristic Raman peak of CAP centered at 1344 cm(−1) was used for the rapid quantitative detection of CAP in three different types of CAP eye drops, and the accuracy of the measurement result was verified by high-performance liquid chromatography (HPLC). The experimental results reveal that the SERS technique based on colloidal Au NPs is accurate and sensitive, and can be used for the rapid detection of various antibiotics. MDPI 2017-12-20 /pmc/articles/PMC5751667/ /pubmed/29261161 http://dx.doi.org/10.3390/s17122962 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ding, Yufeng
Zhang, Xin
Yin, Hongjun
Meng, Qingyun
Zhao, Yongmei
Liu, Luo
Wu, Zhenglong
Xu, Haijun
Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering
title Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering
title_full Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering
title_fullStr Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering
title_full_unstemmed Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering
title_short Quantitative and Sensitive Detection of Chloramphenicol by Surface-Enhanced Raman Scattering
title_sort quantitative and sensitive detection of chloramphenicol by surface-enhanced raman scattering
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751667/
https://www.ncbi.nlm.nih.gov/pubmed/29261161
http://dx.doi.org/10.3390/s17122962
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