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A sparse autoencoder-based deep neural network for protein solvent accessibility and contact number prediction
BACKGROUND: Direct prediction of the three-dimensional (3D) structures of proteins from one-dimensional (1D) sequences is a challenging problem. Significant structural characteristics such as solvent accessibility and contact number are essential for deriving restrains in modeling protein folding an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751690/ https://www.ncbi.nlm.nih.gov/pubmed/29297299 http://dx.doi.org/10.1186/s12859-017-1971-7 |