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How Are Proteins Reduced in the Endoplasmic Reticulum?

The reversal of thiol oxidation in proteins within the endoplasmic reticulum (ER) is crucial for protein folding, degradation, chaperone function, and the ER stress response. Our understanding of this process is generally poor but progress has been made. Enzymes performing the initial reduction of c...

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Detalles Bibliográficos
Autores principales: Ellgaard, Lars, Sevier, Carolyn S., Bulleid, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Trends Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751730/
https://www.ncbi.nlm.nih.gov/pubmed/29153511
http://dx.doi.org/10.1016/j.tibs.2017.10.006