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How Are Proteins Reduced in the Endoplasmic Reticulum?
The reversal of thiol oxidation in proteins within the endoplasmic reticulum (ER) is crucial for protein folding, degradation, chaperone function, and the ER stress response. Our understanding of this process is generally poor but progress has been made. Enzymes performing the initial reduction of c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Trends Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751730/ https://www.ncbi.nlm.nih.gov/pubmed/29153511 http://dx.doi.org/10.1016/j.tibs.2017.10.006 |