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A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm
BACKGROUND: Membranous ventricular septal aneurysm (MVSA) is a rare cardiac anomaly that can occur as an isolated entity or being associated with other cardiac malformations. Complications of MVSA include thromboembolism, arrhythmia, rupture, bacterial endocarditis, right ventricular outflow tract o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751772/ https://www.ncbi.nlm.nih.gov/pubmed/29298686 http://dx.doi.org/10.1186/s12884-017-1646-4 |
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author | Wang, Kana Wang, Xiaodong Yu, Haiyan Liu, Xinghui Xing, Aiyun You, Yong |
author_facet | Wang, Kana Wang, Xiaodong Yu, Haiyan Liu, Xinghui Xing, Aiyun You, Yong |
author_sort | Wang, Kana |
collection | PubMed |
description | BACKGROUND: Membranous ventricular septal aneurysm (MVSA) is a rare cardiac anomaly that can occur as an isolated entity or being associated with other cardiac malformations. Complications of MVSA include thromboembolism, arrhythmia, rupture, bacterial endocarditis, right ventricular outflow tract obstruction, and atrioventricular valve diseases.The success rate of pregnancy and delivery in patients with MVSA has not been reported in the literature. This study was to assess the clinical implications of this condition from our center’s experience. METHODS: This was a retrospective study for consecutive 12 pregnancies in women with MVSA, who delivered at a tertiary care center in west China between May 2008 and March 2015. RESULTS: All patients with MVSA delivered via caesarian section. One patient with severe pulmonary arterial hypertension expired from pulmonary infection and heart failure after delivery. One patient terminated pregnancy in the second trimester- necessitated by cardiogenic shock. The other mothers had varying degrees of cardiac morbidity, but survived. Ten of thirteen newborns survived. Congenital heart disease and small-for-gestational-age (SGA) of newborn occurred in two cases (one twin and one single gestation). Two of these babies expired. CONCLUSIONS: Maternal and neonatal risk appeared associated with heart functional classifications, pulmonary hypertension and histories of cardiac events such as serious cardiac arrhythmia. Accurate diagnosis and care by a multidisciplinary team is recommended for pregnant woman with MVSA. |
format | Online Article Text |
id | pubmed-5751772 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-57517722018-01-05 A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm Wang, Kana Wang, Xiaodong Yu, Haiyan Liu, Xinghui Xing, Aiyun You, Yong BMC Pregnancy Childbirth Research Article BACKGROUND: Membranous ventricular septal aneurysm (MVSA) is a rare cardiac anomaly that can occur as an isolated entity or being associated with other cardiac malformations. Complications of MVSA include thromboembolism, arrhythmia, rupture, bacterial endocarditis, right ventricular outflow tract obstruction, and atrioventricular valve diseases.The success rate of pregnancy and delivery in patients with MVSA has not been reported in the literature. This study was to assess the clinical implications of this condition from our center’s experience. METHODS: This was a retrospective study for consecutive 12 pregnancies in women with MVSA, who delivered at a tertiary care center in west China between May 2008 and March 2015. RESULTS: All patients with MVSA delivered via caesarian section. One patient with severe pulmonary arterial hypertension expired from pulmonary infection and heart failure after delivery. One patient terminated pregnancy in the second trimester- necessitated by cardiogenic shock. The other mothers had varying degrees of cardiac morbidity, but survived. Ten of thirteen newborns survived. Congenital heart disease and small-for-gestational-age (SGA) of newborn occurred in two cases (one twin and one single gestation). Two of these babies expired. CONCLUSIONS: Maternal and neonatal risk appeared associated with heart functional classifications, pulmonary hypertension and histories of cardiac events such as serious cardiac arrhythmia. Accurate diagnosis and care by a multidisciplinary team is recommended for pregnant woman with MVSA. BioMed Central 2018-01-03 /pmc/articles/PMC5751772/ /pubmed/29298686 http://dx.doi.org/10.1186/s12884-017-1646-4 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Wang, Kana Wang, Xiaodong Yu, Haiyan Liu, Xinghui Xing, Aiyun You, Yong A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm |
title | A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm |
title_full | A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm |
title_fullStr | A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm |
title_full_unstemmed | A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm |
title_short | A single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm |
title_sort | single-center experience with 12 consecutive cases of pregnancy among patients with membranous ventricular septal aneurysm |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751772/ https://www.ncbi.nlm.nih.gov/pubmed/29298686 http://dx.doi.org/10.1186/s12884-017-1646-4 |
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