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Hemopexin promotes angiogenesis via up-regulating HO-1 in rats after cerebral ischemia-reperfusion injury
BACKGROUND: Ischemia-reperfusion (I/R) is a critical pathophysiological change of ischemic stroke. Heme-oxygenase-1 (HO-1) is a rate-limiting enzyme of eliminating excessive free heme by combining with hemopexin (HPX), a plasma protein contributing to alleviating infarct size due to ischemia stroke....
Autores principales: | Dong, Beibei, Zhang, Zhishen, Xie, Keliang, Yang, Yongyan, Shi, Yuan, Wang, Chenxu, Yu, Yonghao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751849/ https://www.ncbi.nlm.nih.gov/pubmed/29298658 http://dx.doi.org/10.1186/s12871-017-0466-4 |
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