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Neither non-toxigenic Staphylococcus aureus nor commensal S. epidermidi activates NLRP3 inflammasomes in human conjunctival goblet cells
PURPOSE: The conjunctiva is a wet mucosal surface surrounding the cornea that is continuously exposed to pathogens. Nevertheless, persistent inflammation is not observed. We examined if the NOD-like receptor pyrin domain 3 (NLRP3) inflammasome functions as a sensor that distinguishes commensal and n...
Autores principales: | Li, Dayu, Hodges, Robin R, Bispo, Paulo, Gilmore, Michael S, Gregory-Ksander, Meredith, Dartt, Darlene A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751869/ https://www.ncbi.nlm.nih.gov/pubmed/29354725 http://dx.doi.org/10.1136/bmjophth-2017-000101 |
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