DNA Methylation in Stroke. Update of Latest Advances

Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions su...

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Autores principales: Krupinski, Jerzy, Carrera, Caty, Muiño, Elena, Torres, Nuria, Al-Baradie, Raid, Cullell, Natalia, Fernandez-Cadenas, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2017
Materias:
Short Survey
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751876/
https://www.ncbi.nlm.nih.gov/pubmed/29321829
http://dx.doi.org/10.1016/j.csbj.2017.12.001
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author Krupinski, Jerzy
Carrera, Caty
Muiño, Elena
Torres, Nuria
Al-Baradie, Raid
Cullell, Natalia
Fernandez-Cadenas, Israel
author_facet Krupinski, Jerzy
Carrera, Caty
Muiño, Elena
Torres, Nuria
Al-Baradie, Raid
Cullell, Natalia
Fernandez-Cadenas, Israel
author_sort Krupinski, Jerzy
collection PubMed
description Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field.
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spelling pubmed-57518762018-01-10 DNA Methylation in Stroke. Update of Latest Advances Krupinski, Jerzy Carrera, Caty Muiño, Elena Torres, Nuria Al-Baradie, Raid Cullell, Natalia Fernandez-Cadenas, Israel Comput Struct Biotechnol J Short Survey Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field. Research Network of Computational and Structural Biotechnology 2017-12-09 /pmc/articles/PMC5751876/ /pubmed/29321829 http://dx.doi.org/10.1016/j.csbj.2017.12.001 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Short Survey
Krupinski, Jerzy
Carrera, Caty
Muiño, Elena
Torres, Nuria
Al-Baradie, Raid
Cullell, Natalia
Fernandez-Cadenas, Israel
DNA Methylation in Stroke. Update of Latest Advances
title DNA Methylation in Stroke. Update of Latest Advances
title_full DNA Methylation in Stroke. Update of Latest Advances
title_fullStr DNA Methylation in Stroke. Update of Latest Advances
title_full_unstemmed DNA Methylation in Stroke. Update of Latest Advances
title_short DNA Methylation in Stroke. Update of Latest Advances
title_sort dna methylation in stroke. update of latest advances
topic Short Survey
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751876/
https://www.ncbi.nlm.nih.gov/pubmed/29321829
http://dx.doi.org/10.1016/j.csbj.2017.12.001
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