Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-κB and STAT6 Activation Using a Chimeric Decoy Strategy

Transactivation of inflammatory and immune mediators in asthma is tightly regulated by nuclear factor κB (NF-κB) and signal transducer and activator of transcription 6 (STAT6). Therefore, we investigated the efficacy of simultaneous inhibition of NF-κB and STAT6 using a chimeric decoy strategy to pr...

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Detalles Bibliográficos
Autores principales: Miyake, Tetsuo, Miyake, Takashi, Sakaguchi, Makoto, Nankai, Hirokazu, Nakazawa, Takahiro, Morishita, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751966/
https://www.ncbi.nlm.nih.gov/pubmed/29499930
http://dx.doi.org/10.1016/j.omtn.2017.12.005

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