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A conserved maternal-specific repressive domain in Zelda revealed by Cas9-mediated mutagenesis in Drosophila melanogaster

In nearly all metazoans, the earliest stages of development are controlled by maternally deposited mRNAs and proteins. The zygotic genome becomes transcriptionally active hours after fertilization. Transcriptional activation during this maternal-to-zygotic transition (MZT) is tightly coordinated wit...

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Detalles Bibliográficos
Autores principales:	Hamm, Danielle C., Larson, Elizabeth D., Nevil, Markus, Marshall, Kelsey E., Bondra, Eliana R., Harrison, Melissa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752043/ https://www.ncbi.nlm.nih.gov/pubmed/29261646 http://dx.doi.org/10.1371/journal.pgen.1007120

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