Impaired pentose phosphate pathway in the development of 3D MCF-7 cells mediated intracellular redox disturbance and multi-cellular resistance without drug induction

Although metabolic reprogramming and redox imbalance are widely reported to be involved in chemo-resistance in cancer treatment, much more attention was paid to anti-cancer drug induced effect. Our previous studies showed that cancer cells can develop P-gp overexpression-mediated intrinsic drug resi...

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Detalles Bibliográficos
Autores principales: Wang, Wenjie, Cai, Qingyun, Zhou, Fang, Liu, Jiali, Jin, Xiaoliang, Ni, Ping, Lu, Meng, Wang, Guangji, Zhang, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752090/
https://www.ncbi.nlm.nih.gov/pubmed/29291545
http://dx.doi.org/10.1016/j.redox.2017.12.009

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