C5aR1 promotes acute pyelonephritis induced by uropathogenic E. coli

C5a receptor 1 (C5aR1) is a G protein–coupled receptor for C5a and also an N-linked glycosylated protein. In addition to myeloid cells, C5aR1 is expressed on epithelial cells. In this study, we examined the role of C5aR1 in bacterial adhesion/colonization of renal tubular epithelium and addressed th...

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Detalles Bibliográficos
Autores principales: Li, Ke, Wu, Kun-Yi, Wu, Weiju, Wang, Na, Zhang, Ting, Choudhry, Naheed, Song, Yun, Farrar, Conrad A., Ma, Liang, Wei, Lin-lin, Duan, Zhao-Yang, Dong, Xia, Liu, En-Qi, Li, Zong-Fang, Sacks, Steven H., Zhou, Wuding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752266/
https://www.ncbi.nlm.nih.gov/pubmed/29263309
http://dx.doi.org/10.1172/jci.insight.97626

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