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The AKT inhibitor triciribine in combination with paclitaxel has order-specific efficacy against Zfp217-induced breast cancer chemoresistance

We previously identified the transcription factor ZNF217 (human) / Zfp217 (mouse) as an oncogene and prognostic indicator of reduced survival, increased metastasis, and reduced response to therapy in breast cancer patients. Here we investigated the role of Zfp217 in chemotherapy resistance. Preclini...

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Detalles Bibliográficos
Autores principales:	Suarez, Christopher D., Wu, Junmin, Badve, Sunil S., Sparano, Joseph A., Kaliney, William, Littlepage, Laurie E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752462/ https://www.ncbi.nlm.nih.gov/pubmed/29312549 http://dx.doi.org/10.18632/oncotarget.19308

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