Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

As the expression of a tumor associated antigen (TAA) is commonly not restricted to tumor cells, adoptively transferred T cells modified to express a conventional chimeric antigen receptor (CAR) might not only destroy the tumor cells but also attack target-positive healthy tissues. Furthermore, CAR...

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Detalles Bibliográficos
Autores principales: Mitwasi, Nicola, Feldmann, Anja, Bergmann, Ralf, Berndt, Nicole, Arndt, Claudia, Koristka, Stefanie, Kegler, Alexandra, Jureczek, Justyna, Hoffmann, Anja, Ehninger, Armin, Cartellieri, Marc, Albert, Susann, Rossig, Claudia, Ehninger, Gerhard, Pietzsch, Jens, Steinbach, Jörg, Bachmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752466/
https://www.ncbi.nlm.nih.gov/pubmed/29312553
http://dx.doi.org/10.18632/oncotarget.21017

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